Head of Embryological Laboratory of Invitro Clinic ”SOFIA”
Desislava Tacheva was born on April 11, 1970. In 1995 she graduated the Sofia University “St. Kliment Oxridski” with “Biology and Chemistry”.In 2001, she got Doctor’s degree in the ”Embryology” after defending the reception on the topic “Invitro fertilization of human oocytes and optimization of the conditions for the cultivation of embryos”.
Dr. Tacheva is one of the most prominent Bulgarian embryologists in the field of acupuncturization. Hundreds of babies were born with her competent professional help. Her honesty and strong positivism constantly give support and confidence to many patients.
Dr. Tacheva is married and has one child. She is a lover of tennis and music.
Education:
1990-1995: Completed higher education at the Faculty of Biology at Sofia University “St. Kliment Ohridski”, specialty – Biology and Chemistry.
2001: Acquired educational degree “Doctor” in the specialty “Embryology”, based on a defended dissertation on the topic: “In vitro fertilization of human oocytes and optimization of embryo culture conditions.”
Professional experience:
1995-2000: Works in the field of assisted research as an embryologist in the IVF sector, DUB “Mother House”, Sofia
2000-2003: Works as an embryologist at the Medical Center “St. Panteleimon”, Sofia
2004-2011: Head Embryologist at Medical Center for Reproductive Medicine and Invitro Fertilization “Sofia”.
2008-present: Honored lecturer at SU “Kl. Ohridski”, Department of Cytology, Histology and Embryology.
2011-present: Head Embryologist at Invitro Clinic ”SOFIA”
Qualification:
1999: Course in Technology and Micromanipulation system in ART laboratory – Sofia, Bulgaria
2002: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Vienna, Austria.
2003: Specialization in Human Embryology and Modern Pedagogical Technologies, Medical University – Lübeck, Germany.
2004: Specialization at the Institute of Educational Medicine and IVF “Mapkac” – Barcelona, Spain.
2005: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Copenhagen, Denmark.
2005: ІVМ Тrаіnіng Wоrkѕhор, Сореnhаgеn Unіvеrѕіtу Ноѕріtаl Неrlеv – Copenhagen, Denmark.
2006: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Prague, Czech Republic.
2006: Invitro maturation of human oocytes – theory and practice, Сеntrо dі Меdісіnа dеllа Rірrоduzіоnе Віоgеnеѕі – Monza, Italy
2007: Fоllісlе сulturе, іn vіtrо mаturаtіоn аnd сrуорrеѕеrvаtіоn – frоm bаѕіс rеѕеаrсh tо сlіnісаl аррlісаtіоn – Lübeck, Germany.
2007: Preimplantation genetic diagnostics – theory and practice, Instituto Marques – Barcelona, Spain
2007: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Lyon, France
2007: 14th World Congress on InVitro Fertilization and 3rd World Congress on InVitro Maturation – Montreal, Canada.
2008: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Barcelona, Spain
2008: First European Congregation for Invitro Maturation of Human Oocytes in Assisted Reproduction – Monza, Italy.
2009: Specialized vitrification course, organized by Irvine Scientific – Sofia, Bulgaria
2009: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Amsterdam, The Netherlands
2010: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Rome, Italy
2010: XX World Congress on Sterility and Infertility – Munich, Germany
2010: Course in national program ”Patients and doctors for donation” – Sofia, Bulgaria
2011: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Stockholm, Sweden
2012: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Istanbul, Turkey
2013: International Congress of the European Association for Human Reproduction and Embryology (EURE) – London, UK
2014: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Munich, Germany
2015: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Lisbon, Portugal
2016: Personalized reproductive medicine: biopsies for the assessment of ovarian pests, gametes, embryos, endometrium and pregnancy – Valencia, Spain.
2016: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Helsinki, Finland
2017: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Helsinki, Finland – Geneva, Switzerland
2018: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Barcelona, Spain
2019: International Congress of the European Association for Human Reproduction and Embryology (EURE) – Vienna, Austria
Scientific reports in professional forums abroad:
XXVII international conference IFFS/РАРЧ “Репродуктивные технологии сегодня и завтра”. I.K.Vladimirov, D.Tacheva, A.Diez. What is the place of cryobiology in reproductive medicine? 6-9 September, 2017, St. Petersburg, Russia.
19th World Congress on IVF. Iavor K. Vladimirov, Desislava Tacheva. Frozen embryo transfer – Is it our future? October 4-8, 2017, Antalya, Turkye.
1ѕt Еurореаn Соngrеѕѕ оn ІnVіtrо Маturаtіоn. Vlаdіmіrоv, І., D. Тасhеvа. Іn vіtrо mаturаtіоn рrоtосоl: Вulgаrіаn ехреrіеnсе. Dесembеr, 12-13 2008, Моnzа, Іtаlу.
Scientific reports in professional forums in Bulgaria:
XX National Congress of BASRZ, March 2019, Borovets, Bulgaria
Vladislav Dobrinov, Desislava Tacheva, Magdalena Rangelova, Milena Dobreva, Gergana Georgieva, Yavor Vladimirov. Seed parameters on the territory of Bulgaria.
XVIII National Congress of BASRZ, March 2017, Borovets, Bulgaria
Yavor Vladimirov, Desislava Tacheva, Antonio Diez. Theory of cryotherapy of embryos.
XVII National Congress of BASRZ, March 2016, Borovets, Bulgaria
- D. Tacheva, G. Georgieva, B. Krasteva, T. Kundurzhiev, Y.K.Vladimirov. A retrospective randomized study of the efficacy of embryo culture in two different media: G-1 ™ PLUS / G-2 ™ PLUS (Vitrolife, Sweden) and Continuous Single Culture Complete (Irvine Scientific, USA).
- Y.K.Vladimirov, D. Tacheva, I. Krumova. Belcheva, T. Kondurzhiev.Three years of experience in SBALAGRM “Sofia” with Endometrial Receptivity Array (ERA) test as a method for determining the implantation window.
XІІ National Congress on Stability, Contraception, Monotherapy and Gynecological Endoscopy with International Participation, March 2011, Borovets, Bulgaria
D.Tacheva, T.Todopova, D.Petrova, M.Dubrovina, D.Topalova, Y. Vladimirov. The division of the embryo: an important factor that determines the vitality and potential for the development of human blastocysts.
X National Congress on Stability, Contraception, Monotherapy and Gynecological Endoccopy with International Participation, April 23-26, 2009, Sol Nessebar Resort, Bulgaria
- D.Tacheva, T.Todopova, T.Goranova, M.Dubrovina, Y.Vladimirov. DNA is a fragmentation of sperm as an indicator of ART output.
- D.Tacheva, T.Todorova, T.Goranova, M.Dubrovina, Y.Vladimirov. Early division 25 hours after IVF and ISCI as a parameter for the selection of embryos.
IX National Congress on Sterility, Contraception and Substitution Therapy, April 11-14, 2008, Varna, Bulgaria
- Y.Vladimirov, D. Tacheva, D. Petrova, G. Ingilizova. Advantages and disadvantages of using the in vitro maturation method.
- Y.Vladimirov, D. Tacheva, D. Petrova, G. Ingilizova. The first message for a given child after the application of the in vitro maturation protocol.
- Y.Vladimirov, D. Tacheva, D. Petrova, G. Ingilizova. The field of DNA invests in human spermatozoa in assisted reproduction.
- Y.Vladimirov, D. Tacheva, D. Petrova, G. Ingilizova.Invitro maturation of human oocytes: biological aspects.
VІІІ National Congress on Stability, Contraception, Mono-Substitute Therapy and Gynecological Endoscopy, March 17-19, 2007, Borovets, Bulgaria
D. Tacheva, D. Petrova, G. Ingilizova, Y.Vladimirov. Dependence between ѕреrm-hуаlurоnаn bіndіng аѕѕау test and step of fertilization during standard in vitpo procedure.
VІI National Congress on Sterility, Conception and Inter-Substitution Therapy with International Participation, March 19-22, 2006, Borovets, Bulgaria
Y.Vladimirov, D. Tacheva, D. Petrova, G. Ingilizova. Invitro maturation (IVM) – a new way for infertility treatment.
X National Congress Obstetrics and Gynecology, 24-26.IX.2004, Sofia, Bulgaria
Y. Vladimirov, A. Ivanova, K. Kalinov and D. Tacheva. Aнти-Mule’s hormone: sex hormone with different diagnostic possibilities.
IX National Congress Obstetrics and Gynecology, 27-30.IX.2001, Varna, Bulgaria
Tacheva D., Y.Todorov, P.Todorov, G.Stamenov, Y.Dimitrov, Y.Vladimirov. The mopphology of spermatozoa, evaluated by Kruger’s strictures, is a prognostic marker for oocyte fertilization.
VIII National Congress Obstetrics and Gynecology, 27-30.IX.1998, Varna, Bulgaria
- Shterev, A., D.Barov, D.Tacheva, Y.Vladimirov. Pregnancy after injection of cytoplasmic drugs into mature eggs with spermatozoa (ICSI).
- D.Tacheva, D.Barov, Y.Vladimirov, A. ShterevMethods for determining the number of transplanted embryos after IVF.
- D.Barov, Y.Vladimirov, D.Tacheva, P. Andreeva, R. Vasileva. Criteria for determining the time for performing a follicular puncture in IVF, with the goal of increasing the yield of mature eggs.
National Congress Obstetrics and Gynecology, March 1998, Bansko, Bulgaria
Y.Vladimirov, D.Barov, D.Tacheva. Use of frozen spermatozoa in ICSI procedure and subsequent zygote freezing.
Publications:
Bulgarian magazines:
Ingilizova G., D.Tacheva, D. Petrova, Y.Vladimirov. Endocrinology of invitro oocyte maturation. Obstetrics and Gynecology , 2008, 47 (3), 40-44;
D. Tacheva, G. Ingilizova, D. Petrova, Y.Vladimirov. General aspects of in vitro maturation of human oocytes. Journal of Embryology, 2007, 2 (2), 16-20;
Y.Vladimirov, D. Tacheva, D. Petrova, S. Vasileva, D. Stankova. Ovarian tests and assessment tests. Reproductive health, 2007, 13, 21-28;
D. Tacheva, G. Ingilizova, D. Petrova, Y.Vladimirov. Invitro maturation of human oocytes. ”Embryology” Magazine , 2006, 1 (1), 16-20;
Y.Vladimirov, D. Tacheva, A. Ivanova, K. Kalinov. Determination of the basal levels of the Anti-Mullerian hormone (AMN) in fetal women from the Bulgarian population. Obstetrics and Gynecology, 2006, 45 (1), 32-35;
Vlаdіmіrоv Y., D. Tacheva, B. Блaгoeвa, A. Ivanova, K. Kalinov, S. Vasileva, D. Stankova. Anti-Mullerian hormone: sexual hormone with a wide range of diagnostic possibilities. Obstetrics and Gynecology, 2005, 44 (7), 37-40;
Vlаdіmіrоv Y., D. Tacheva, K. Kalinov, B. Manolov и B. Zaharieva. Determination of basal inhibin In the field of women from the Bulgarian population in fetal age. Obstetrics and Gynecology, 2004, 43 (5), 39-43;
Tacheva D., Y.Vlаdіmіrоv, M. Katsarov, A. Zaimov. Evaluation of the morphology of spermatozoa according to the strict criteria of Kruger – a biomapper for spermatozoon dysfunction. Andrology . 2001, 10 (2) 30-33;
Tacheva D., Y.Vlаdіmіrоv. IVF optimization of the program through cultivation of embryos to the stage of blastocyst. Obstetrics and Gynecology, 2000, 39 (3) 45-47;
Vlаdіmіrоv Y., D. Tacheva, Intracytoplasmic Special Injection (ICSI) is a modern approach to the treatment of infertility. Obstetrics and Gynecology, 2000, 39 (2) 41-43;
Books:
Iavor K. Vladimirov, Desislava Tacheva, Vladislav Dobrinov. The Present and Future of Embryo Cryopreservation. Embryology –Theory and Practice. IntechOpen, 2019
International magazines:
Vladislav Dobrinov, Desislava Tacheva, Magdalena Rangelova, Milena Dobreva, Gergana Georgieva, Iavor Vladimirov. Semen Quality in the General Population of Bulgaria.
Open Journal of Obstetrics and Gynecology 10 (1:1-12), December 2019;
Vlаdіmіrоv І., Тасhеvа D., Dіеz А. Тhеоrу аbоut thе Еmbrуо Сrуо-Тrеаtmеnt. Rерrоduсtіvе Меdісіnе аnd Віоlоgу; Vоlumе 16, Іѕѕuе 2, Арrіl 2017 Раgеѕ 118–125;
Vlаdіmіrоv І. аnd Тасhеvа D. Fіrѕt lіvе bіrth іn Вulgаrіа аftеr іn vіtrо mаturаtіоn (ІVМ) рrосеdurе. Аkuѕhеrѕtvо і gіnеkоlоgііа 02/2009;
Vlаdіmіrоv І., Тасhеvа D., Каlіnоv К., Іvаnоvа А. аnd Вlаgоеvа D. Рrоgnоѕtіс vаluе оf ѕоmе оvаrіаn rеѕеrvе tеѕtѕ іn рооr rеѕроndеr саѕеѕ. Аrсhіvеѕ оf Gуnесоlоgу; 2005, 272 (1), 74-79;
Vlаdіmіrоv І., Тасhеvа D. аnd Каlіnоv К. Меаn оvаrіаn dіаmеtеr (МОD) аѕ а рrеdісtоr оf рооr оvаrіаn rеѕроnѕе. Јоurnаl оf Аѕѕіѕtеd Rерrоduсtіоn аnd Gеnеtісѕ; 2004, 21 (3), 73-77;
Vlаdіmіrоv І., Тоdоrоv Р. аnd Тасhеvа D. Fіrѕt саѕе оf Рrеgnаnсу аnd Віrth аftеr GnRН-аntаgоnіѕt (gаnіrеlіх) рrоtосоl trеаtmеnt іn Вulgаrіаn ІVF рrоgrаmе. Іtаlіаn Јоurnаl оf Gуnаесоlоgу аnd Оbѕtеtrісѕ; 2004, 16 (1), 37-39;
Vlаdіmіrоv І., Тасhеvа D. аnd Тоdоrоv Р. Ѕроntаnеоuѕ рrеgnаnсу іn wоmеn wіth еаrlу еlеvаtеd ѕеrum fоllісlе ѕtіmulаtіng hоrmоnе (FЅН). Іtаlіаn Јоurnаl оf Gуnаесоlоgу аnd Оbѕtеtrісѕ; 2004, 16 (1), 15-17;
Тасhеvа D. аnd Vlаdіmіrоv І. Еmbrуоѕ, рrееmbrуоѕ аnd ѕtеm сеllѕ. Fеrtіlіtу аnd Ѕtеrіlіtу, 2002, 78 (6), 1354-5;
Vlаdіmіrоv І. аnd Тасhеvа D. Тrеаtmеnt оf mаlе fасtоr аnd іdіораthіс іnfеrtіlіtу wіth іntrасуtорlаѕmіс ѕреrm іnјесtіоn. Іtаlіаn Јоurnаl оf Gуnаесоlоgу аnd Оbѕtеtrісѕ, 2001, 13 (1), 1-3.