NACE пренатална диагностика


NACE® - Non-invasive prenatal test alternative to amniocentesis

NACE® is a non-invasive prenatal test. This means that it is completely safe for you and your baby. A small blood sample taken from the arm, just like in any other routine blood analysis, is sufficient to run the test. NACE uses the latest sequencing technology to analyze fetal DNA compared to maternal DNA to detect certain anomalies with high precision and reliability.

Human beings have 23 pairs of chromosomes with a total of 46 (two copies of each pair). Health and development issues appear if there is a missing or extra chromosome. When there is an additional copy of a chromosome (i.e. three copies instead of two), it is called a trisomy. NACE is a complete prenatal test to detect anomalies in chromosomes 21, 18, and 13 (Down, Edwards, and Patau syndromes). It also detects the most common anomalies in the sexual chromosomes X and Y (Except for twin gestations). Tha NACE test detects foetuses with chromosomal anomalies with very high precision.

The NACE test is recommended for women who want to rule out the most commonly detected fetal chromosomal alterations without putting their pregnancy at risk. It is especially recommended for women with a high risk of chromosomal abnormalities after first trimester screening, those with previous Down syndrome pregnancies, or to detect any alterations suspected from ultrasounds. NACE can also be used by women whose pregnancy was achieved via in vitro fertilization, including gestations resulting from donated oocytes. The NACE test is valid for single and twin* gestations.

Innovative prenatal screening NACE® was first applied in Bulgaria at the Sofia Hospital of Obstetrics, Gynaecology and Reproductive Medicine.