Treatment

ALICE test

ALICE Analysis of Infectious Chronic Endometritis


ALICE detects the bacteria causing chronic endometritis to improve your patient’s reproductive outcome.

What is ALICE test?

  • ALICE is a test that detects pathogenic bacteria and recommends adequate treatment.
  • Pathogenic bacteria cause chronic endometritis, which is linked to implantation failure and recurrent miscarriage.
  • In cases of repeated implantation failure or recurrent pregnancy loss, chronic endometritis can rise to 66%.

What is the procedure?

Why use ALICE test?

  • ALICE is a diagnostic test to detect and quantify the most common pathogenic bacteria causing chronic endometritis., recommending appropriate antibiotic and probiotic treatment.
  • ALICE microbiology method allows the identification of culturable and nonculturable endometrial pathogens associated with chronic endometritis.
  • A list with the recommended antibiotics and probiotics will be provided depending on ALICE results.
  • ALICE may also be beneficial for patients with a history of recurrent pregnancy loss or recurrent implantation failure because chronic endometritis has been linked to these events.
  • If ALICE tests positive, the report will focus on the detection of those the specific bacteria causing said the condition.
  • Microbiology counseling will be available.

Who should use ALICE test?

  • ALICE can be beneficial for any patient wishing to conceive, by assessing the microbiological environment that the embryo will encounter at implantation.
  • ALICE may also be beneficial for patients with a history of recurrent pregnancy loss or recurrent implantation failure because chronic endometritis has been linked to these events.

Test Limitations

  • This test are not able to detect resistance to antibiotics. 
  • ALICE only detects the presence of pathogens associated with chronic endometritis. A negative result does not rule out the presence of other endometrial pathogens. 
  • The tests are not 100% accurate at determining the bacterial species. 
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