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Iavor Vladimirov, MD, PhD

Medical Director, Sofia IVF Clinic


1990: Medicine at the Medical University, Sofia

1997: Specialised in Obstetrics and Gynaecology

2003: Wrote a thesis on Diagnostic Testing to Determine Egg Reserves in Infertile Females and obtained a Doctorate at the Obstetrics and Gynaecology Department in the Sofia Medical University



1990 to 1991: Emergency practitioner at Varshets

1991 to 1992: Assisted Reproduction Intern at the “Maychin Dom” University Hospital in Sofia

1993 to 1997: Clinical Practitioner at the “Maychin Dom" University Hospital in Sofia, Obstetrics and Gynaecology Department

1998 to 1999: Obstetrician and Gynaecologist at the “Sveti Dimitar” IVF Centre in Sofia

2000 to 2003: Obstetrician and Gynaecologist at the “Sveti Panteleymon” Medical Centre in Sofia

2004 to 2011: Manager at the “Sofia” IVF Clinic

2008-present: Lecturer at the Sofia University “St.Kliment Ohridski”, Department of Cytology, Histology and Embryology

2011-present: Medical Director at the SBALAGRM “Sofia”



1993: Breast Care Course in Sofia

1993: Ultrasound in Obstetrics and Gynaecology Course in Sofia

1993: Abdominal and Transvaginal Ultrasound Diagnostics Course in Sofia

1995: Colposcopy Course in Sofia

1996: International Ultrasound School, Ohrid

1996: International IVF Technology Symposium, Salonica

1997: PostgraduatestudiesinReproductiveEndocrinologyandInVitro Fertilisation at the Reinier de Graaf  University Hospital, the Hague

1999: Course in Basic Micro Manipulation Techniques and Use at ART Laboratorii, Sofia

2001: Postgraduate studies in Reproductive Endocrinology and In Vitro Fertilisation at the Tel Aviv Medical University, Israel

2001: Endoscopy Course, Sofia

2002: International Symposium on GnRH Antagonists in Lübeck, Germany

2002: The European Society of Human Reproduction and Embryology (ESHRE) congress, Vienna, Austria

2003: International Symposium onGnRH-Analogues and Human Reproduction, Amsterdam

2004: Symposium on Gonadotropins from Basic Research to Clinical Practice, Munich

2005: The European Society of Human Reproduction and Embryology (ESHRE) congress, Copenhagen

2005: IVM Training Workshop, Copenhagen University Hospital Herlev, Copenhagen

2005: Serono Symposia International conference: Endometrium and Embryo Implantation, Paris

2006: The European Society of Human Reproduction and Embryology (ESHRE) congress, Prague

2006: In Vitro Maturation of Human Oocytes: Theory and Practice, Centro di Medicina della Riproduzione – Biogenesi, Monza

2007: Follicle Culture, In Vitro Maturation and Cryopreservation: from Basic Research to Clinical Application, Lübeck

2007: The European Society of Human Reproduction and Embryology (ESHRE) congress, Lyons

2007: The 14th World Congress of In Vitro Fertilisation and the 3rd World Congress of In Vitro Maturation, Montréal

2008: The 9th International Serono Symposium: GnRH Antagonists, Berlin

2008: ESHRE Campus Workshop: Egg Reserves, Modena

2008: The European Society of Human Reproduction and Embryology (ESHRE) congress, Barcelona

2008: The First European Congress on In Vitro Maturation of Human Oocytes in Assisted Reproduction, Monza

2009: CourseinAssistedReproductiveTechniques, VrijeUniversiteitBrussel, Brussels

2009: The European Society of Human Reproduction and Embryology (ESHRE) congress, Amsterdam

2010: The European Society of Human Reproduction and Embryology (ESHRE) congress, Rome

2010: The 20th World Congress in Sterility and Infertility, Munich

2010: Training Course under the Patients and Physicians for Donoring National Programme, Sofia

2011: The European Society of Human Reproduction and Embryology (ESHRE) congress, Stockholm

2012: The European Society of Human Reproduction and Embryology (ESHRE) congress, Istanbul

2013: The European Society of Human Reproduction and Embryology (ESHRE) congress, London

2014: The European Society of Human Reproduction and Embryology (ESHRE) congress, Munich

2015: The European Society of Human Reproduction and Embryology (ESHRE) congress, Lisbon

2016: The 3rd Biomarker Meeting in Personalized Reproductive Medicine: Biomarkers for the Assessment of Ovarian reserve, Gametes, Embryos, Endometrium and Pregnancy, Valencia


International Publications

1. Vladimirov I., Tacheva D., Diez A. Theory about the Embryo Cryo-Treatment. Reproductive Medicine and Biology; Volume 16, Issue 2, April 2017 Pages 118–125;

1. C. Simon, I.K. Vladimirov, G. Castillon Cortes, I. Ortega, S. Cabanillas, C. Vidal, J. Giles, A. Izquierdo, S. Portela, I. Fernandez, M. Ferrando, S. Mackens, S. Barrera, A. Pellicer. Prospective, randomized study of the endometrial receptivity analysis (ERA) test in the infertility work-up to guide personalized embryo transfer versus fresh transfer or deferred embryo transfer. Fertility and Sterility; 09/2016, 106 (3), e46–e47;

2. Ruiz Alonso M., Diaz-Gimeno P., Gomez E., Rincin-Bertolin A., Vladimirov I., Garrido N., Simon C. Clinical efficiency of emryo transfer performed in receptive vs non-receptive endometrium diagnosed by the endometrial receptivity (ERA) test. Fertility and Sterility; 10/2014, 102 (3), 292;

3. Broer S.L., Dolleman M., van Disseldorp J., Broeze K.A., Opmeer B.C., Bossuyt P.M.M., Eijkemans M.J.C, Mol B.W., Broekmans F.J.M., Aflatoonian A., [...], Multikrishna S., Nardo L.G., Nelson S.M., Ng H.Y., Popovic-Todorovic B., Smeenk J.M.J., Tomas C., Van der Linden P., van Rooij I, Vladimirov I. Prediction of an excessive response in in vitro fertilization  from patient characteristics and ovarian  reserve tests and comparison in subgroups: An individual patient data meta-analysis. Fertility and Sterility; 08/2013, 100 (2), 420-429;

4. Broer S.L., van Disseldorp J., Broeze K.A., Dolleman M., Opmeer B.C., Anderson R.A., Ashrafi M., Bancsi L., Caroppo E., Copperman A, [...], Popovic-Todorovic B., Smeenk J.M.J., Tomas C., Van der Linden P.J., van Rooij I.A., Vladimirov I., Bossuyt P.B., Eijkemans M.J.C., Mol B.W.J., Broekmans F.J.M. Added value of ovarian reserve testing on patient characteristics in the prediction of ovarian response and ongoing pregnancy: An individual patient data approach. Human Reproduction Update; 02/2013, 19 (1), 26-36;

5. Vladimirov I,and Tacheva D, First live birth in Bulgaria after in vitro maturation (IVM) procedure,Obstetrics and Gynecology, 02/2009

6. Vladimirov I,Tacheva D, Kalinov K, Ivanova A,Blagoeva D,“Prognostic Value of Some Ovarian Reserve Tests in Poor Responder Cases,Archives of Gynecology, 2005, 272 (1), pp 74–79

7. Vladimirov I, Tacheva D,Kalinov K,“Mean Ovarian Diameter (MOD) as a Predictor of Poor Ovarian Response,Journal of Assisted Reproduction and Genetics, 2004, 21 (3), pp 73–77

8. Vladimirov I, Todorov P,Tacheva D,“First Case of Pregnancy and Birth after GnRH–Antagonist (Ganirelix) Protocol Treatment in Bulgarian IVF Programme,”Giornale Italiana di Ginecologia e Ostetricia, 2004, 16 (1), pp 37–39

9. Vladimirov I, Tacheva D,Todorov P,“Spontaneous Pregnancy in Women with Early Elevated Serum Follicle Stimulating Hormone (FSH),”Giornale Italiana di Ginecologia e Ostetricia, 2004, 16 (1), pp 15–17

10. Tacheva D andVladimirov I,“Embryos, Preembryos and Stem Cells,”Fertility and Sterility, 2002, 78 (6), pp 1354–5

11. Vladimirov I.“The Future for Aromatase Inhibitors is Bright,”Fertility and Sterility, 2002, 78 (5), p 1141

12Vladimirov I and Tacheva D,“Treatment of Male Factor and Idiopathic Infertility with Intracytoplasmic Sperm Injections,”Giornale Italiana di Ginecologia e Ostetricia, 2001, 13 (1), pp 1–3.


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