In the case of artificial insemination, hatching of the embryo includes spontaneous disintegration of the membrane, which envelops the egg. In this way, the embryo releases and prepares for implantation in the uterus. In some cases, this membrane is abnormally thick and does not allow the embryo to hatch. It is believed that the lack of implantation of the embryo is due to the impossibility of attaching the pellicide zone. This means that the embryo cannot be implanted in the uterus. The problem is most common in more aging women, although it can be observed in any single group.
The assisted hatching of the embryo is a micromanipulation method, which is most often used in embryos at the stage of 6-8 cells. It is assumed that the opening through the micromanipulation of the opening in the zone helps the hatching and the actual interaction between the embryo and the embryo.
Laser-assisted hatching (LАН)
The appearance of the laser has led to the development of precise techniques for manipulating the embryos, in order to improve fertility. Laser-assisted hatching of the embryos can drastically change history of unsuccessful implantation of embryos in the uterine wall. Invitro Clinic ”SOFIA” offers the latest generation of equipment for laser-assisted hatching of embryos LYКОЅ™ from Наmіltоn Тhоrnе, Іnс – a leading world-class supplier of laser equipment for reproductive medicine.
Laser assisted hatching (LАН) c LYКОЅ™ uses highly focused infrared laser beam, which removes the pellicide zone at very precise steps. Beforef LYКОЅ™ technology, only mechanical or chemical methods could be used for hatching of embryos. Laser-assisted hatching requires less manipulation of the embryo than other methods of assisted hatching. Also, laser-assisted hatching is faster than other methods and because of this, the embryo spends less time outside the incubator.
What are the indications for LАН?
LАН is not recommended as a routine procedure for all IVF patients. When choosing candidates for LАН, few factors are considered. These include age, hormonal status, quality of the embryos, number if invitro experiments, as well as whether freezed embryos are being implanted.
- Age: Women over 37 years
- hormonal status: Women with higher basic level of FЅN
- Quality of embryos: Women with embryos with poor prognosis, including conditions such as a thick zone of pellicide, slow division of cells or a high percentage of fragmentation of fertility
- Number of IVF experiments: Women with 1 or more unsuccessful tries
- Frozen embryos: Women using frozen /thawed embryos, which may have a hardened pellicide zone.